evaluation of three rubella vaccines in conferring protection

نویسندگان

k. naficy

r. nategh

m. khakpour

m. mohagheghpour

چکیده

the effeminacy of three rubella vaccines, hpv/77 ide-5, cendehill-51 and wistar ra/27/3 in conferring immunity against untenanted rubella virus was compared. vaccination resulted in 90-100 percent protection against clinical rubella. intranasal challenge with the untenanted strain of rubella virus resulted in serologic evidence of in apparent reinfection in three of the ten cendehill-51 vaccines the virus was isolated from the throat specimens of two, and one developed adenopathy. two of the eleven ra/27/3 vaccines became reinfected. virus was isolated from the throat specimen of one and a booster response occurred in that other; the latter developed rash. all of the hpv/177/de-5 vaccines remained symptom less after the challenge. none demonstrated booster response and shed virus.

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عنوان ژورنال:
iranian journal of public health

جلد ۳، شماره ۳، صفحات ۱۱۷-۱۲۷

کلمات کلیدی
[ ' r u b e l l a v a c c i n e s ' , ' h p v / 7 7 i d e ' , 5 , ' c e n d e h i l l ' , 5 1 , ' w i s t a r r a / 2 7 / 3 ' , ' i r a n ' ]

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